Chemical Products Acyclovir Product Usage

CAS No:59277-89-3

Formula:C8H11N5O3

Synonyms:Acyclovir Tablets

China Export:From 2018.11 to 2019.11, total export volume of Acyclovir from China was 112,377,052KG while total export value was $2,146,929,254. The biggest proportion of exporting volume in the last 12 months was 9.88% in 2019.03.


Chemical Products Acyclovir Description

Acyclovir, a molecule tailored to inactivate the thymidine kinase of the herpesvirus, is a guanosine analogue antiviral drug. It is a drug for HSV infection by GlaxoSmithKline.IC50 Value: 0.53-0.75 uM [3]Target: HSVin vitro: Acyclovir sensitivity was determined in a plaque-reduction assay in Vero cells. IC50 Values were consistently 2-3 fold lower in B2 compared with the H strain of Vero cells. HSV Type 2 strains were 2-10-fold less sensitive than Type 1 strains [2]. in vivo: two patient


Chemical Products Acyclovir Basic Attributes

CAS No：59277-89-3


Molecular Formula ：C8H11N5O3


Molecular Mass ：225.2


Exact Mass ：225.086182


PSA ：115 A^2


LogP ：-1.6


EINECS ：261-685-1


InChIKeys ：MKUXAQIIEYXACX-UHFFFAOYSA-N


H-bond Acceptor ：4


H-bond Donor ：3


RBN ：4


Chemical Products Acyclovir Characteristics

Appearance ：white powder


Density ：1.8±0.1 g/cm3


Melting Point ：256-257°C


Bolling Point ：595°C at 760 mmHg


Flash Point ：302.4±32.3 °C


Refractive Index ：1.762


Solubility ：soluble in 1M HCl at 50mg/ml. soluble in water at 0.7mg/ml. Also soluble in DMSO


Storage Condition ：−20°C


Vapor Pressure ：5.4X10-15 mm Hg at 25 deg C (est)


Stability ：Stable. Incompatible with strong oxidizing agents.





Chemical Products Acyclovir Safety Information

Hazard Class ：IRRITANT


HS Code ：2933990090


UN No. ：NONH for all modes of transport


WGK_Germany ：2


Risk Code ：36/37/38-40-20/21/22


Safety Instructions ：22-24/25-36-26-23


RTECS No. ：UP0791400


Dangerous Mark ：Xi,Xn


Storage ：Treasury is ventilated, low temperature and dry; stored separately from food materials


P Code ：P201, P202, P264, P270, P280, P281, P301+P312, P302+P352, P308+P313, P312, P322, P330, P363, P405, P501


Hazard Statements ：H302


Flammability ：Flammable; burning releases toxic nitrogen oxide fumes; drug side effects; allergic dermatitis, dreams, fantasy


Toxicity ：Subcutaneous-rat LD50: 620 mg/kg; peritoneal-rat LD50: 860 mg/kg


Toxicity Class ：moderately


Chemical Products Acyclovir Product Usage

Orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. AntiviralBroad-spectrum antiviral drugs, containing purine nucleus compounds, are converted into triphosphate compounds in the body, interfere with viral DNA polymerase, inhibit viral DNA replication and play an antiviral effect. It has a strong effect on the virus. It is used for the prevention and treatment of viral skin or mucous membrane infections, as well as hepatitis B, herpes simplex keratitis, varicella zoster virus infection, etc.


Chemical Products Acyclovir Material and Products

Material ：

Adenine, 9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine, 6-Hydroxypurine, Activated carbon, 1,3-Dioxolane, 1,4-DIACETOXYBUTANE, Methylamine methanol, 6-Methoxyguanine, Guanine, TRIMETHYLSILANE, P-Toluenesulfonic Acid, Sodium Nitrite

评论

发表评论

此博客中的热门博文

oak bedroom furniture maintenance methods

  oak bedroom furniture maintenance methods The maintenance methods of oak bedroom furniture mainly include the following points: ‌ Avoid dust and hard objects friction: ‌ regularly clean the surface of the furniture, ‌ to avoid dust accumulation, ‌ at the same time avoid using sharp objects scratch the surface of the furniture, ‌ when placing heavy objects is best padded with soft cloth, ‌ to protect the paint and texture of the furniture. ‌ Control the indoor humidity: ‌ to keep the indoor humidity appropriate, ‌ to avoid furniture shrinkage due to low humidity or high expansion, ‌ affect the service life and beauty of furniture. ‌ Keep away from corrosive liquids: ‌ avoid furniture contact with corrosive liquids, ‌ such as chemical cleaners, ‌ so as not to damage the surface of furniture. ‌ Avoid the sun: ‌ prolonged exposure to sunlight can cause fading of furniture, ‌ therefore avoid placing furniture in direct sunlight, ‌ or use curtains and other shading items to reduce UV dama
阅读全文

chemical companies use ERP software to improve profitability

图片
When choosing enterprise resource planning (ERP) solutions, chemical companies are faced with some special challenges related to work style and financial tracking. However, as long as there are suitable partners, chemical companies can use the extraordinary advantages of ERP software platform to improve efficiency and profitability. Ten years ago, ERP solutions were less flexible and did not provide the industry specificity needed to be fully effective. However, today's solutions have a wide range of features and specific details that chemical companies need to succeed. ERP solution is a platform integrating various manufacturing components, including operation, finance, human resources, supply chain, sales and marketing. By storing and sharing data in a single system, employees in chemical companies can better understand customer relationships, make more informed decisions in real time, and develop new cooperation opportunities within and between suppliers. The following is a det
阅读全文

Procurement problems faced by chemical suppliers

图片
Purchasing is the core of any large organization. Finding the raw materials you need at the right price is the key to keep your business going. In the complex and delicate world of the chemical industry, there are very few chemical suppliers who meet all the requirements. The following are seven common procurement problems faced by chemical suppliers: 1. More competition and greater complexity You're not afraid of competition, but you don't want them to have the upper hand in getting the best sources of chemicals. The industry is complex and demanding, and so are your orders. You need a chemical supplier who fully understands your complex needs and meets them every time. 2. It will exceed the budget It's much easier than we're willing to admit. Overspending can have direct and serious consequences, affecting credit lines, disrupting profit forecasts, and stopping further purchases. Although this situation can usually be remedied, it is important to make the procurement
阅读全文